Yin says believe, but Yang won't let him.
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Drug Makers in shift
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Seems that a simpler way would be to add an inert and easily detected chemical marker to the drugs. This has been done with other things I believe, such as explosives.
"To be free and to live a free life - that is the most beautiful thing there is."
Miguel Indurain -
I'd say the Howman interview I linked here is probably closer to reality.
http://forums.competitor.com/topic/47130
The wise man said follow me...and he walked behind. -
Cost of FDA approval of an easily detected chemical that can be injected into humans of all sorts with no biologic effect: millions. If such a chemical even exits, which I doubt. Rare but potentially fatal reactions can occur with almost any chemical when introduced into the human body.
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rnddude, LSD has it mostly right. The abused drugs are mostly injectables. US and European regulations prohibit most additives to parenterals. Tablets and capsules can have colors and flavors added, but they are not allowed in parenterals. Stabilizers, such as preservatives, stabilizers, and chelators, have to be extensively justified. Exposing a targeted patient to extra risk in order to control inappropriate use is just not ethical.
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To add to lsd's point: that chemical better not have adverse consequences to the extremely sick and physically vulnerable patients (the target market for EPO for example).
Ben
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What exactly is the target market for EPO? I believe there have been some legit questions about that raised given that volumes of production far exceed needs from the "supposed" target market, the sick.
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OC- I am curious to see your sources for the questions. In any case, Pharma can only market for approved uses. Any off-label use is up to physicians' discretion. They may welcome the off-label use, but cannot push it. Some companies have gotten into a mess of trouble for promoting off-label use, especially if adverse events pop up.
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Smokey, there is a book out that details the huge amount of EPO/ ProCrit that was sold and I think the book asserts that a large amount went off-label. I haven't read the book but it's on my list.
Blood Medicine: Blowing the Whistle on One of the Deadliest Prescription Drugs Ever
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Smokey, WADA has done a fair bit of poking on the subject:
"...EPO rapidly became one of the pharmaceutical substances with the largest sales, and this induced a massive overproduction, far beyond the real requirements of patients. This overproduction, estimated at about five to six times the treatment requirements, is supported by the very startling theft of phials, which occurred in 1999 in Nicosia (Cyprus)..."
http://www.wada-ama.org/rtecontent/document/donati_report_trafficking_2007-03_06.pdf
The interview Howman gave the other week is also insightful:
http://www.reuters.com/article/2013/02/12/us-doping-wada-howman-idUSBRE91B14L20130212
more money is made out of selling drugs to high school children than to elite athletes.
"Most of the supplements around the world that you see come from the United States. And we know only too well because we have seen some of the more recent supplements intentionally include performance-enhancing components because they want to get a bit of an edge with the markets that they are servicing,"
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After Congress fixes firearms, they can then address doping in sports. In the meantime, cheaters will still try to cheat.
Put the focus on testing, don't leak results, and make the penalties really count.
Depending on your viewpoint, peds were overlooked, tolerated, or tacitly encouraged for the past few decades. It won't be changed over night
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